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Regulation of the thrombin/protease-activated receptor 1 axis by chemokine  (CXC motif) receptor 4
Regulation of the thrombin/protease-activated receptor 1 axis by chemokine (CXC motif) receptor 4

Research Sahar El Aidy lab
Research Sahar El Aidy lab

Tango assay for ligand-induced GPCR–β-arrestin2 interaction: Application in  drug discovery - ScienceDirect
Tango assay for ligand-induced GPCR–β-arrestin2 interaction: Application in drug discovery - ScienceDirect

Molecular insights into intrinsic transducer-coupling bias in the  CXCR4-CXCR7 system | bioRxiv
Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system | bioRxiv

Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas  system | Nature Communications
Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system | Nature Communications

PRESTO-Tango as an open-source resource for interrogation of the druggable  human GPCRome | Nature Structural & Molecular Biology
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome | Nature Structural & Molecular Biology

Addgene: PTGER2-Tango
Addgene: PTGER2-Tango

PRESTO-Tango as an open-source resource for interrogation of the druggable  human GPCRome | Nature Structural & Molecular Biology
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome | Nature Structural & Molecular Biology

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a  GPCR-Wide Scale using PRESTO-Tango Assay | Protocol
Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay | Protocol

Design of the Tango assay. ( A ) A schematic of the Notch signaling... |  Download Scientific Diagram
Design of the Tango assay. ( A ) A schematic of the Notch signaling... | Download Scientific Diagram

PRESTO-Tango as an open-source resource for interrogation of the druggable  human GPCRome | Nature Structural & Molecular Biology
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome | Nature Structural & Molecular Biology

A piggyBac-based TANGO GFP assay for high throughput screening of GPCR  ligands in live cells | Cell Communication and Signaling | Full Text
A piggyBac-based TANGO GFP assay for high throughput screening of GPCR ligands in live cells | Cell Communication and Signaling | Full Text

Addgene on Twitter: "Hot Plasmids | PRESTO-TANGO kit Bryan Roth lab-  parallel analysis to assay GPCR activation https://t.co/3wHXXrbnCT  https://t.co/puB1kebOmN" / Twitter
Addgene on Twitter: "Hot Plasmids | PRESTO-TANGO kit Bryan Roth lab- parallel analysis to assay GPCR activation https://t.co/3wHXXrbnCT https://t.co/puB1kebOmN" / Twitter

A piggyBac-based TANGO GFP assay for high throughput screening of GPCR  ligands in live cells | Cell Communication and Signaling | Full Text
A piggyBac-based TANGO GFP assay for high throughput screening of GPCR ligands in live cells | Cell Communication and Signaling | Full Text

Multiplexed profiling of GPCR activities by combining split TEV assays and  EXT-based barcoded readouts | Scientific Reports
Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts | Scientific Reports

A piggyBac-based TANGO GFP assay for high throughput screening of GPCR  ligands in live cells | Cell Communication and Signaling | Full Text
A piggyBac-based TANGO GFP assay for high throughput screening of GPCR ligands in live cells | Cell Communication and Signaling | Full Text

Dose-dependent effects of prazosin and cyclazosin in PRESTO-Tango... |  Download Scientific Diagram
Dose-dependent effects of prazosin and cyclazosin in PRESTO-Tango... | Download Scientific Diagram

Addgene: DRD2-Tango
Addgene: DRD2-Tango

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a  GPCR-Wide Scale using PRESTO-Tango Assay | Protocol
Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay | Protocol

PRESTO-Tango as an open-source resource for interrogation of the druggable  human GPCRome | Nature Structural & Molecular Biology
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome | Nature Structural & Molecular Biology

Addgene on Twitter: "Roth Lab @UNC PRESTO-Tango Plasmid Kit to measure  activation of >300 #GPCRs https://t.co/OdJ07r7iEO  https://t.co/r45qLbdEUE" / Twitter
Addgene on Twitter: "Roth Lab @UNC PRESTO-Tango Plasmid Kit to measure activation of >300 #GPCRs https://t.co/OdJ07r7iEO https://t.co/r45qLbdEUE" / Twitter

Tango assay for ligand-induced GPCR–β-arrestin2 interaction: Application in  drug discovery - ScienceDirect
Tango assay for ligand-induced GPCR–β-arrestin2 interaction: Application in drug discovery - ScienceDirect

PRESTO-Tango as an open-source resource for interrogation of the druggable  human GPCRome | Nature Structural & Molecular Biology
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome | Nature Structural & Molecular Biology

A piggyBac-based TANGO GFP assay for high throughput screening of GPCR  ligands in live cells | Cell Communication and Signaling | Full Text
A piggyBac-based TANGO GFP assay for high throughput screening of GPCR ligands in live cells | Cell Communication and Signaling | Full Text

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a  GPCR-Wide Scale using PRESTO-Tango Assay | Protocol
Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay | Protocol

Recent progress in assays for GPCR drug discovery | American Journal of  Physiology-Cell Physiology
Recent progress in assays for GPCR drug discovery | American Journal of Physiology-Cell Physiology